Extended Data Fig. 3: Chromosomal integration events of transfected plasmids containing a retention element are stochastic and occur at near-background levels.
From: Genetic elements promote retention of extrachromosomal DNA in cancer cells
Genome-wide read coverage (non-overlapping 50 kb bins) and detection of chromosomal integration events (events per bin) of transfected plasmids in single-molecule long-read nanopore sequencing from cells transfected with either an empty plasmid vector (pUC19; top) or plasmid containing a retention element (pUC19_RE-C; bottom).
