Fig. 4: Relative effect of mutational processes.
From: Somatic evolution following cancer treatment in normal tissue
a, The relative effect of four different processes. Left to right: the number of SSB5 mutations per year of ageing in different tissues; the number of ageing years equivalent to 40 pack years; 6 cisplatin cycles; and 50 drink years in different tissues. b, Example mutation accumulation plots showing how different mutational processes may result in mutations in different tissues over time. c, Mutation accumulation plots across tissues from three individuals. d, Fraction of mutations attributed to exogenous mutational processes across tissues. Each dot represents one sample.
