Fig. 1: NeuMap, an integrative map of the neutrophil transcriptome.
a, Scheme of the tissues and biological conditions used to generate NeuMap using scRNA-seq. Further details in Supplementary Table 1. b, UMAP visualization by tissue of origin. c, Score value of gene sets for specific biological processes. Complete gene lists in Supplementary Table 2. APC, antigen-presenting cell; OxPhos, oxidative phosphorylation. d, UMAP visualization of neutrophils extracted from health or diseased conditions. e, Scheme of the functional compartmentalization of NeuMap. Each hub is defined by areas containing the top 85% K-mass score. f, Stacked bars showing the proportion of cells from different organs and conditions in each transcriptional hub. Please note that not all 47 conditions are included in the panel. Tissues from healthy young male and female mice are labelled in red, and treatments or disease for each tissue are indicated at the bottom of each bar.
