Extended Data Fig. 1: NeuMAP, a map of the neutrophil transcriptome. | Nature

Extended Data Fig. 1: NeuMAP, a map of the neutrophil transcriptome.

From: Architecture of the neutrophil compartment

Extended Data Fig. 1

(A) Plots showing the sorting strategy to isolate neutrophils from the indicated tissues. Note the different gating for the bone marrow. (B) Evolution of the NeuMAP by the cumulative addition of neutrophils from the indicated tissues. (C) Score expression on the NeuMap of published gene sets associated with neutrophil differentiation and maturation. (D) Score values of genes expressed in primary, secondary, and specific granules onto the NeuMAP. (E) K-mass score of neutrophils by the indicated tissue of origin in the NeuMAP. (F) Contour plots of the combined neutrophils from the indicated tissues in various conditions of disease. (G) Contour plots of the combined neutrophils from the indicated tissues of males, females, and old (80 week-old) individuals. (H) Mapping of neutrophils from the indicated studies, showing their distribution in the NeuMap.

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