Extended Data Fig. 4: Increased width of the corpus callosum following deletion of TSC1/2 in intermediate progenitors. | Nature

Extended Data Fig. 4: Increased width of the corpus callosum following deletion of TSC1/2 in intermediate progenitors.

From: TSC tunes progenitor balance and upper-layer neuron generation in neocortex

Extended Data Fig. 4: Increased width of the corpus callosum following deletion of TSC1/2 in intermediate progenitors.The alternative text for this image may have been generated using AI.

(A,D) Consistent with the increase in upper layer neurons (tdTomato+) in TSC1/2Tbr2 cKO, the width of the corpus callosum (arrow), containing the axonal projections of these neurons, is increased. (E) Quantification of increased width of tdTom labeled corpus callosum (CC). Data shown are mean ± SEM (n = 10 mice/group). Unpaired two-sided t-test; ***p < 0.0001. Scale bar: A-D (100 μm).

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