Extended Data Fig. 3: Contribution of mutational signatures to major driver genes.
From: Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma
a, Single base substitution (SBS) mutational patterns for the driver mutations of EGFR, KRAS, and TP53. b, Distribution of all driver mutations and hotspot mutations (recurrence > 5) in EGFR, KRAS, and TP53 attributed to each mutational signature.
