Fig. 5: Gut microbial SGBs that increase after dietary interventions are linked to more favourable ZOE MB health- and diet-ranks.
From: Gut micro-organisms associated with health, nutrition and dietary interventions
a, The 20 most significant gut microbial SGBs with the greatest effect sizes following the BIOME dietary intervention from Fig. 4a (left), paired with their ZOE MB health-ranks and diet-ranks, if available (right). b, The 20 most significant gut microbial SGBs with the greatest effect sizes following the METHOD personalized dietary intervention programme from Fig. 4b (left), paired with their ZOE MB health-ranks and diet-ranks, if available (right). The x axis shows the log2-transformed ratio of mean relative abundance SGB values at endpoint over baseline. All values are reported in Supplementary Table 25. c,d, The distributions of the ZOE MB health-ranks (c) and diet-ranks (d) for the prebiotic blend arm of the BIOME cohort (n = 57 of tested SGBs). e,f, The distributions of the ZOE MB health-ranks (e) and diet-ranks (f) for the PDP arm of the METHOD cohort (n = 46 of tested SGBs). The distributions show that SGBs increasing in relative abundance have significantly more favourable ranks, whereas decreasing SGBs have more unfavourable ranks (two-sided Mann–Whitney U-test, P = 7.78 × 10−3, P = 3.00 × 10−5, P = 5.20 × 10−5 and P = 2.03 × 10−5, respectively). Distributions of the ZOE MB health-ranks and diet-ranks for the other arms are reported in Extended Data Fig. 10e,f. Box plots as in Fig. 1.
