Extended Data Fig. 1: GPCRs induce both GTP binding and release from Gα proteins and the process is ligand dependent. | Nature

Extended Data Fig. 1: GPCRs induce both GTP binding and release from Gα proteins and the process is ligand dependent.

From: GTP release-selective agonists prolong opioid analgesic efficacy

Extended Data Fig. 1

Shown are the radioactivity counts (dpm) without normalization. Means with s.e.m are plotted, and the parameters are presented with 95% CI in Fig. 1, MOR: n = 6 binding, 5 release; KOR: n = 3 binding, 5 release; 5HT1AR: 8 binding, 7 release; M2 n = 3 binding, 3 release; SST2: n = 4 binding, 4 release. Accompanies Fig. 1.

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