Extended Data Fig. 10: ACC neurons are selective for valence, nociception. | Nature

Extended Data Fig. 10: ACC neurons are selective for valence, nociception.

From: Mimicking opioid analgesia in cortical pain circuits

Extended Data Fig. 10: ACC neurons are selective for valence, nociception.

(a,c) Activity of all recorded neurons across stimuli, sorted to hot water- (a) or sucrose- (c) evoked activity (n = 4 mice). (b,d) Average activity of significantly hot water- (b) or sucrose- (d) suppressed (top) and -activated (bottom) neurons during each stimulus. (e) Average fraction overlap of stimulus-activated (left) and -suppressed (right) neurons. (f) Average Fisher decoding accuracy of sensory stimuli. (g) Permutation test p-values within each animal testing if Fisher decoding accuracy for stimuli is significantly higher than chance in each session (n = 1000 shuffles). (h) auROC of Fisher decoder in each animal in real and shuffled data. Dots are individual animals.

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