Extended Data Fig. 2: Somatic landscape of all acral melanoma samples, one selected per patient (n = 91). | Nature

Extended Data Fig. 2: Somatic landscape of all acral melanoma samples, one selected per patient (n = 91).

From: Ancestry and somatic profile indicate acral melanoma origin and prognosis

Extended Data Fig. 2: Somatic landscape of all acral melanoma samples, one selected per patient (n = 91).

a) Oncoplot depicting the seven most mutated genes according to dNdScv and five selected genes based on mutational frequency and biological function. Mutational classification, sample type, tumour stage, sex, age at diagnosis, ulceration status, tumour site and mutational spectra are shown by sample. Primary samples were selected preferentially for this analysis. One sample where no mutations were detected is not depicted in the oncoplot. b) Mutations found in PTPRJ, ATM, NF2 and RDH5, for which all mutations are deleterious and are found altered each in two samples.

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