Extended Data Fig. 4: Significantly altered regions per sample by GISTIC analysis. | Nature

Extended Data Fig. 4: Significantly altered regions per sample by GISTIC analysis.

From: Ancestry and somatic profile indicate acral melanoma origin and prognosis

Extended Data Fig. 4: Significantly altered regions per sample by GISTIC analysis.

Top panel. Number of significant regions altered by sample. Bottom panel. Binary heatmap showing the significantly altered regions identified by GISTIC2 per sample. One sample per patient is shown. Heatmap is ordered on the X axis by mutational classification and on the Y axis by frequency of alterations per region. As a note, sample PD41002a does not show a deletion in CDKN2A (Deletion peak 3) by GISTIC2 analysis, but a deletion was detected by CNVkit (Methods, Extended Data Fig. 1).

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