Extended Data Fig. 10: Casein-only diet allows for stronger anti-peanut responses.
From: Environmentally driven immune imprinting protects against allergy
(a) Experimental scheme. Breeder pairs (BALB/cJ) were kept on casein-only diet and progeny were weaned and maintained on casein-only diet for the duration of the experiment. Upon reaching adulthood, mice were injected subcutaneously with cOVA or peanut extract and then challenged systemically. (b) Maximum core body temperature loss in mice after cOVA sensitization and challenge (n = 10). (c) Maximum core body temperature loss in mice after peanut extract sensitization and challenge (n = 20). Statistical significance was determined using one-way ANOVA with Tukey correction for multiple comparisons against regular chow and soy-free data presented in Fig. 4. Error bars represent SD. Data are pooled from two or more repeats of each experiment.
