Fig. 2: EBV DNA is a biomarker of complex traits. | Nature

Fig. 2: EBV DNA is a biomarker of complex traits.

From: Population-scale sequencing resolves determinants of persistent EBV DNA

Fig. 2

a, Summary of associations between EBV DNAemia and binary phenotypic traits in the UKB, with individuals of broadly NFE ancestry. The horizontal dashed line represents the phenome-wide significant P-value threshold (3.3 × 10−6). The y axis is capped at –log10(P) = 50, with those exceeding this threshold plotted at 50. Union phenotypes are plotted to reduce redundancy. Selected traits are highlighted based on biological interest. Statistical test: Wald test from logistic regression model (two-sided). b, Effect sizes for matching ICD-10 codes between the UKB and AOU, with individuals of European ancestry in AOU. Dotted lines at odds ratio = 1 represent null associations. Sample size: n = 426,563 UKB NFE individuals; n = 133,578 for AOU European ancestry individuals. The colours are the same as in a.

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