Extended Data Fig. 2: Supporting analyses of EBV DNA detected from WGS data from AOU.
From: Population-scale sequencing resolves determinants of persistent EBV DNA
(a) Schematic of AOU chrEBV extraction from blood-based WGS. (b) Sum of per-base read coverage of map quality (MAPQ) score ≥30. (c) Partition of AOU participants by EBV DNA detection after accounting for biased regions, the same as in Extended Data Fig. 1c. (d) Percent EBV DNAemia resolved by sex and age in AOU. Statistical test: two-sided proportion test. Error bars: standard error of the mean. (e) Percent EBV DNAemia resolved by genetic ancestry in AOU. (f) Percent EBV DNAemia resolved by sex and immunosuppressive drug use in AOU. Statistical test: two-sided proportion test comparing sex in the associated immunosuppressive drug use bin. Error bars: standard error of the mean. For panels c,d,e,f: center is the mean or point estimate of the proportion; error bars: standard error of the mean. Sample size: n = 245,394. The silhouettes in panel a were adapted from ref. 19, Springer Nature Ltd.
