Extended Data Fig. 4: Supporting analyses for NFE genetic association studies from UKB.
From: Population-scale sequencing resolves determinants of persistent EBV DNA
(a) Partitioned heritability enrichment via stratified LD score regression. Shown are the 9 genomic features with positive heritability enrichment at a nominal P < 0.05. Statistical test: two-sided LD score regression full model. Center of bar: point estimate; error bars: standard errors of mean. Sample size: summary statistics from 426,563 NFE individuals. (b) Concordant effect sizes for non-MHC genome-wide suggestive (P < 1 × 10−5; two-sided likelihood ratio test) variants assayed in both the GWAS and ExWAS. Comparison: 43 genetic variants associated at P < 1 × 10−5 in both the ExWAS and the GWAS.
