Extended Data Fig. 10: Cell cycle arrest at different stages and perturbation of autocatalytic wave competition in zebrafish embryo.
From: Robust cytoplasmic partitioning by solving a cytoskeletal instability
a Cell cycle arrest in syncytial zebrafish embryo at 16 cell stage. b Cell cycle arrest in syncytial zebrafish embryo at 32 cell stage. c Cell cycle arrest in syncytial zebrafish embryo at thousands cell stage. d Microtubule density profiles across the interface during an invasion event in a zebrafish embryo arrested at 8 cell stage (Fig. 4f). e Microtubule density profiles across the interface during an invasion event in arrested extract in a droplet showing similar dynamics to the zebrafish embryo (Fig. 4j). f Microtubule density profiles across the interface during the invasion event in a zebrafish embryo arrested at 32 cell stage (b). In the case of smaller aster, the invasion event resembles the ones observed in “unconfined” extract. g Left: Live imaging of interphase-arrested zebrafish embryo where oil droplets were injected. Right: Plot of the microtubule density interface shown in dashed green over time. h Left: Live imaging of interphase-arrested zebrafish embryo treated with microtubule depolymerizing drug. Right: Plot of the microtubule density interface shown in dashed green over time. i Left: Live imaging of interphase-arrested zebrafish embryo treated with dynein inhibitor. Right: Plot of the microtubule density interface shown in dashed green over time.
