Extended Data Fig. 2: Sequencing depth in CNV loci.
From: Developmental convergence and divergence in human stem cell models of autism
Whole genome sequencing depth in (a) 16p11.2 (b) 15q13.3 (c) 22q11.2 and (d) 22q13.3 loci averaged over 10 kb windows. (e) Mutational forms not shown in main figure showing genes inside the CNV locus or genes carrying the point mutations (marked in blue). Genes significantly differentially expressed over all time points are denoted by asterisks (dreamlet p-values of p < 0.005). The percent of DE genes in the CNV across the 4 time points is as follows: 22q13del - 77.3% of genes, 22q11del - 88.9% of genes.
