Extended Data Fig. 8: Lipid binding assay for purified STING.
From: Regulation of STING activation by phosphoinositide and cholesterol
(a) Binding of wild-type STING to a panel of lipids in a lipid-strip assay. (b) Binding of wild-type STING to an array of cholesterol and derivatives. (c) Comparison of binding to PIPs between wild-type STING and the K20E/R71H mutant. (d) Comparison of cholesterol binding between wild-type STING and the S80I mutant. The data shown are representative of three biological repeats.
