Table 1 Association results for the rs112233623-T variant

From: Reduced cyclin D3 expression in erythroid cells protects against malaria

Trait

Number of samples

Genotype count (CC/CT/TT)

MAF

Effect (β)

Standard error

P value

HbA2 (g dl−1)

6,762

5,480/1,219/63

0.099

0.306

0.032

4.03 × 10−22

MCH

6,824

5,526/1,234/64

0.1

0.319

0.031

2.48 × 10−24

MCV

6,824

5,526/1,234/64

0.1

0.356

0.032

3.77 × 10−29

RBC

6,819

5,521/1,234/64

0.1

−0.267

0.032

1.18 × 10−16

HbF (g dl−1)

6,710

5,436/1,211/63

0.099

0.091

0.032

4.32 × 10−3

HbA1 (g dl−1)

6,708

5,434/1,211/63

0.099

0.003

0.032

0.932

  1. Tests for association of rs112233623-T with haematological phenotypes measured in the SardiNIA cohort. The table reports, from left to right, the trait tested; the number of samples (n) included in the analysis for each trait; the genotype count; the MAF; the effect size (β) expressed in standard deviation units, and its standard error; and the P value.
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