Extended Data Fig. 7: Neurosynth meta-analytic transmodal-unimodal axis aligns with the SA axis and consolidates across development. | Nature

Extended Data Fig. 7: Neurosynth meta-analytic transmodal-unimodal axis aligns with the SA axis and consolidates across development.

From: Functional hierarchy of the human neocortex across the lifespan

Extended Data Fig. 7: Neurosynth meta-analytic transmodal-unimodal axis aligns with the SA axis and consolidates across development.

a, Canonical axis A derived from 24 Neurosynth term maps parcellated with the Schaefer-400 atlas: each term map was z-scored across parcels and A = z(ZassocZuni). Warm colours indicate transmodal cortex; cool colours indicate unimodal (sensorimotor/visual) cortex. b, Example term z-maps illustrating unimodal (somatosensory, tactile) and transmodal (task switching, theory of mind) topographies. c, Individual-level similarity to A versus age (Spearman ρ between A and each individual’s SA gradient). Points denote individuals; the curve shows a GAMM fit with a 95% s.e. band. df, Lifespan distributions of term–axis alignment for SA (d), VS (e) and MR (f): for each term and axis, alignment was computed as the parcel-wise Spearman correlation between the standardized term map and each individual’s axis map. Box plots show the median and interquartile range; whiskers indicate the 5th–95th percentiles; terms are ordered by median alignment. In cf, n = 3,972.

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