Fig. 3: Global gradient metrics denote changes in hierarchical FC architecture across the lifespan.
From: Functional hierarchy of the human neocortex across the lifespan
a, Inter-vigintile gradient range versus age with GAMM fits for the SA, VS and MR axes. b, Gradient dispersion versus age with GAMM fit. c, Cosine similarity between individual gradients and the template gradient set used for alignment. d, FC degree versus gradient dispersion; black line shows an ordinary least squares linear regression with 95% confidence interval for the mean. Association was quantified using a Pearson product–moment correlation (two-sided): r = 0.455 (95% confidence interval: 0.430–0.479), P = 2.79 × 10−202 (no multiple-comparisons adjustment). e, Mean FC degree across the lifespan with GAMM fit. Across all panels, n = 3, 972 gradient sets. Solid lines show population-level GAMM fits; shaded ribbons indicate 95% pointwise confidence intervals of the fitted mean.
