Extended Data Fig. 5: Commensal E. coli Nissle (EcN) primed immunogenicity cross-reactive to other Enterobacteriaceae.
From: Natural maternal immunity protects neonates from Escherichia coli sepsis
a, IgG end point EcEPT titres against each bacterial or fungal species in the serum of adult mice 50 days after oral EcN inoculation (n = 7–8 mice/group, with each dot representing the data from an individual animal) compared with control mice without E. coli colonization (n = 6–7 mice/group, with each dot representing the data from an individual animal). b, Sequence alignment for each OmpA outer loop peptide across multiple E. coli strains or Enterobacteriaceae species. Data are presented as mean values (bar) ± one standard deviation. Differences between groups analysed using unpaired Student’s t test.
