Extended Data Fig. 7: scDRS analysis as in Fig. 3, using more fine-grained cell annotation. | Nature

Extended Data Fig. 7: scDRS analysis as in Fig. 3, using more fine-grained cell annotation.

From: Host control of persistent Epstein–Barr virus infection

Extended Data Fig. 7: scDRS analysis as in Fig. 3, using more fine-grained cell annotation.

a) UMAP representation plot of the 1M-scBloodNL data (v3) colored according to cluster labels of cell type annotation level 2. b) Distribution of normalized single-cell disease relevance scores (scDRS) across cell types of annotation level 2, sorted according to the largest average score. White bars indicate the median scDRS. c) Results of the Monte Carlo (MC)-based statistical inference of cell type association (left) and within-cell type heterogeneity (right) with scDRS based on EBVread+. Bar colors represent significance, with purple color indicating a multiple comparison-adjusted false discovery rate (FDR) < 0.05. Further information is provided in Methods and Fig. 3.

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