Extended Data Fig. 5: Correlation of GS-based EBV-reads and individual measurements of four EBV-related antibodies. | Nature

Extended Data Fig. 5: Correlation of GS-based EBV-reads and individual measurements of four EBV-related antibodies.

From: Host control of persistent Epstein–Barr virus infection

Extended Data Fig. 5: Correlation of GS-based EBV-reads and individual measurements of four EBV-related antibodies.

7,338 individuals of the UKB EUR cohort were seropositive for EBV, based on the detection of at least 2 out of 4 EBV-related antibodies. For IgG antibodies against a) EA-D, b) EBNA-1, c) VCA-p18 and d) ZEBRA, individuals were assigned to deciles based on median fluorescence intensity (MFI), and the deciles were tested for significant correlation with the 0/1-encoded EBVread+ status using Spearman correlation coefficients (ρ) and two-sided P-values (P). **Exact P value not available due to computational limits. Bar sizes indicate overall fractions of EBVread+ individuals within the respective deciles (left y-axis), with colors representing different EBV read count groups (legend on bottom). Dots represent average MFI values per decile (right y-axis labels). Analysis was performed on raw measurement data, without adjustment for covariates.

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