Extended Data Fig. 4: Categorization of cell types from unit features and tone response by cell type. | Nature

Extended Data Fig. 4: Categorization of cell types from unit features and tone response by cell type.

From: Plasticity and language in the anaesthetized human hippocampus

Extended Data Fig. 4: Categorization of cell types from unit features and tone response by cell type.The alternative text for this image may have been generated using AI.

a. The tone response was significant in a larger proportion of interneurons than pyramidal cells (pyramidal cells: 46.7% responders; interneurons: 73.6% responders; p = 0.0142, chi-squared test). In the tone/oddball experiment (Figs. 2 and 3), we classified 45.3% of cells as pyramidal cells, 51.2% of cells as narrow interneurons, and 3.5% of cells as wide interneurons using conventional analysis tools (CellExplorer) based on their spike waveform and autocorrelogram features. In the language analysis (Fig. 4), we classified 65.3% of cells as pyramidal cells, 24.6% of cells as narrow interneurons, and 10% of cells as wide interneurons. b. Each subplot shows the plots the firing rate over time (mean ± SEM across cells) in response to tones. Vertical box: duration of the tone response. Shaded area is the mean ± SEM across all cells.

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