Supplementary Figure 7: Additional PROCISiR combinations for two-location control of NS3.
From: Multi-input chemical control of protein dimerization for programming graded cellular responses
a, Colocalization of GNCR1-BFP or DNCR2-EGFP with NS3a-mCherry-CAAX after treatment with danoprevir (5 µM), grazoprevir (5 µM), or DMSO. b, Colocalization of NS3a-mCherry with Tom20-BFP-ANR or DNCR2-EGFP-CAAX after treatment with danoprevir (5 µM), grazoprevir (5 µM), or DMSO. Images are representative of two separate wells and the number of cells given in Supplementary Table 3. c,d, The mean (marked by dot) and standard deviation (error bars) of the Pearson’s r of red/blue or red/green pixel intensities for the number of cells stated in Supplementary Table 3 is given for each condition in (a,b), along with the distributions of Pearson’s r.
