Supplementary Figure 6: Predicted nucleosome occupancy.
From: Deciphering eukaryotic gene-regulatory logic with 100 million random promoters
(a,b) Model predicts nucleosome occupancy well. (a) Model predicted (x axis) vs. measured (MNase-Seq, y axis) nucleosome occupancy. Four MNase biological replicates are shown (Methods). (Blue lines: Generalized Additive Model lines of best fit.) (b) As in (a), with replicates averaged, and only promoters present in both replicates shown. (c) Model-predicted accessibility across the YGR012W locus. A genome browser track showing yeast genes (top), measured nucleosome occupancy (Zhang, second from the top) and DNaseI hypersensitivity (Hesselberth, third from the top), and model predicted accessibilities (Ω). Promoters are predicted to be accessible and models provide similar predicted accessibilities. The four models were learned independently from different experimental data.
