Extended Data Fig. 4: Allele frequency tables of DNA on-target editing by SPACE. | Nature Biotechnology

Extended Data Fig. 4: Allele frequency tables of DNA on-target editing by SPACE.

From: A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing

Extended Data Fig. 4

Composition of alleles with frequencies of 1% or higher that result from SPACE editing with 27 gRNAs (HEK site 2 data shown in Fig. 1d). Data are taken from the first replicate obtained for each gRNA from the on-target experiment shown in Fig. 1b. Numbering indicates the position in the protospacer with 1 being the most PAM-distal location.

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