Extended Data Fig. 5: Apoptotic marker expression in epithelial cells. | Nature Biotechnology

Extended Data Fig. 5: Apoptotic marker expression in epithelial cells.

From: COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

Extended Data Fig. 5: Apoptotic marker expression in epithelial cells.The alternative text for this image may have been generated using AI.

a, Comparison of apoptosis marker gene expression in the different epithelial cell types of critical and moderate COVID-19 cases as well as controls. Asterisks above critical violins indicate p-values for the comparison of critical vs. control samples, asterisks above moderate indicate the comparison moderate vs. control. *: p < 0.05, **: p < 0.01, ***: p < 0.001. p-Values were obtained from a negative-binomial test and Benjamini-Hochberg corrected. Exact p-values are shown in b. Only upregulation is shown, no significant downregulation was observed. b, Table indicating p-values and log fold changes of markers of the extrinsic apoptotic cascade (FAS, CASP8) in epithelial cell populations (for other apoptotic markers see Fig. 3e). The respective comparison, critical vs. control and moderate vs. control, is indicated (n = 5 control, 14 moderate, 13 critical samples).

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