Extended Data Fig. 10: SNV density and MAG strain heterogeneity.
From: A unified catalog of 204,938 reference genomes from the human gut microbiome
a, Correlation between the SNV density calculated among MAGs and their level of strain heterogeneity estimated with CMseq (n = 268,994 comparisons). A Pearson correlation test was performed to determine the correlation coefficient and P value. Colors denote density of data points (increasing from dark purple to yellow). b, Comparison of pairwise SNV density between isolates (n = 808,331 comparisons) and between MAGs with <0.01% (n = 2,923,610 comparisons) and <0.1% strain heterogeneity (n = 13,634,222 comparisons). A two-tailed Wilcoxon rank-sum test was performed to assess statistical significance and further adjusted for multiple comparisons using the Benjamini-Hochberg correction (***P <0.001). Box lengths represent the IQR of the data, and the whiskers the lowest and highest values within 1.5 times the IQR from the first and third quartiles, respectively.
