Extended Data Fig. 9: Ad-Cre infection does not lead to leaky neoantigen expression. | Nature Biotechnology

Extended Data Fig. 9: Ad-Cre infection does not lead to leaky neoantigen expression.

From: Inducible de novo expression of neoantigens in tumor cells and mice

Extended Data Fig. 9

Quantification of endogenous H2Db/GP33-43-specific Thy1.2+CD8+ cells from the spleen (gray dots) and draining LNs (white dots) of NINJA mice 8 days after S.C. infection in the footpad with the indicated mixes of Ad-FLPo + Ad-Cre or Ad-FLPo + Ad-GFP (total dose 107 PFU/mouse) was performed by flow cytometry. Representative experiment is shown (n = 5). n.s. = difference not significant by two-tailed unpaired t test for comparisons of (Ad-FLPo + Ad-Cre) vs. (Ad-FLPo + Ad-GFP) responses in the spleen (P = 0.9) and in the draining LNs (P = 0.3). Average values ± SD are shown.

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