Extended Data Fig. 5: Biosynthetic Gene Cluster Analysis. | Nature Biotechnology

Extended Data Fig. 5: Biosynthetic Gene Cluster Analysis.

From: Generating lineage-resolved, complete metagenome-assembled genomes from complex microbial communities

Extended Data Fig. 5

The HiFi assembly revealed approximately 25% more complete Biosynthetic Gene Clusters (BGCs) than the average pCLR assembly (a). This increase was manifested in all identified BGC classes (colors in legend) and was not exclusive to one particular class. As found in other metagenome assembly datasets, the majority of identified BGCs were novel in all assemblies (b), but the HiFi assembly had a higher proportion of novel BGCs than the other assemblies. Additionally, the HiFi assembly contained more partial BGCs (c) of any assembly.

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