Extended Data Fig. 3: Product purity for PPE, PPE-∆RNase H, PPE-NC-v1, and ePPE.
From: An engineered prime editor with enhanced editing efficiency in plants
(a) Product purity in prime editing by PPE, PPE-∆RNase H, PPE-NC-v1, and ePPE at 12 endogenous sites in rice protoplasts. Frequencies (means ± s.e.m.) were calculated from three independent experiments (n = 3). (b) Fold-change in the observed prime editing edit:byproduct ratio for 12 rice target sites. Values were calculated from the data presented in Fig. 2c. Data and error bars reflect the mean and standard deviation of three independent biological replicates. Frequencies (means ± s.e.m.) were calculated from three independent experiments (n = 3).
