Table 1 Mean F1 scores of the compared segmentation methods on our samples

From: Deep Visual Proteomics defines single-cell identity and heterogeneity

Sample

Method

 

M1

M2

M3

OUR

U2OS cyto

0.0667* ± 0.0075

0.5994 ± 0.0262

0.7205 ± 0.0152

0.7336 ± 0.0218

Melanoma nuc

0.1126 ± 0.0151

0.4386 ± 0.0157

0.1801 ± 0.0504

0.5498 ± 0.0231

Melanoma cyto

0.0058* ± 0.0021

0.0549 ± 0.0083

0.4859 ± 0.0354

0.5536 ± 0.0625

Salivary gland nuc

0.0797 ± 0.0138

0.6488 ± 0.0430

0.0338 ± 0.0145

0.7684 ± 0.0316

Salivary gland cyto

0.0714* ± 0.0151

0.0793 ± 0.0167

0.3174 ± 0.0588

0.5051 ± 0.0586

Melanoma (pink) nuc

0.0682 ± 0.0183

0.2999 ± 0.0599

0.0364 ± 0.0238

0.5079 ± 0.0392

Melanoma (pink) cyto

0.0261* ± 0.0070

0.0865 ± 0.0213

0.2659 ± 0.0429

0.2839 ± 0.0229

Fallopian tube nuc

0.0006 ± 0.0009

0.3121 ± 0.0501

0.3160 ± 0.0631

0.4724 ± 0.0683

Fallopian tube cyto

0.0016* ± 0.0023

0.0671 ± 0.0208

0.4566 ± 0.0530

0.3455 ± 0.0473

  1. The methods are as follows: M1 is unet4nuclei6, M2 is CellProfiler8, M3 is Cellpose7 and OUR refers to nucleAIzer3 (implemented in BIAS). High scores are highlighted in bold. Asterisks (*) mark that M1 is intended for nucleus segmentation but was applied to segment cytoplasm. s.e.m. is displayed with ± after the mean F1 scores in each cell.