Extended Data Fig. 1: Spatial genome alignment on 1 Mb seqFISH+ chromatin imaging of mESCs.
From: A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH
(a) Heatmaps of seqFISH+ chromatin imaging of mouse embryonic stem cells (mESCs) at 1 Mb kb resolution (bottom left) juxtaposed to contact frequency from bulk proximity ligation assay or Hi-C binned at 25 kb (top right), continued from Fig. 2. (b) Spearman correlation between pairwise spatial distances (x-axis; log-normalized) imaged at 25 kb resolution against Hi-C contact frequency (y-axis; log-normalized) binned at 1 Mb resolution.
