Fig. 1: De novo, cell-type-specific prediction of 3D chromatin organization with C.Origami. | Nature Biotechnology

Fig. 1: De novo, cell-type-specific prediction of 3D chromatin organization with C.Origami.

From: Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening

Fig. 1

a, A schematic of C.Origami architecture. b, C.Origami integrates DNA sequence, CTCF ChIP–seq and ATAC–seq signals as input features to predict Hi-C interaction matrix in 2-Mb windows. Concat, concatenation; Conv1D, one-dimensional convolution; Conv2D, two-dimensional convolution; res-block, residual network block.

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