Extended Data Fig. 7: Genome-wide comparison of de novo prediction quality in GM12878.

For de novo prediction results from each model (Akita, DeepC, Orca and C.Origami), we measured insulation score correlation (a), observed versus expected Hi-C matrices correlation (b), mean squared error (MSE) (c) and distance-stratified correlation (d). Prediction results at cell-type-specific regions between IMR-90 and GM12878 cells were selected for this analysis. Error bars in the violin plots indicate minimum, mean and maximum values within each group.