Extended Data Fig. 8: Experimental design for the parabiosis study and variance analysis of samples.

(A) Schematic plot of the experimental aging intervention and heterochronic parabiosis. Visualization of all samples of the parabiosis cohort over all detected non-coding features in a t-SNE, colored by tissue (B, color code as indicated in Fig. 1a) and treatment group (C, color code as indicated in Fig. 4b).