Fig. 6: Allogeneic HIP islets achieve long-term survival. | Nature Biotechnology

Fig. 6: Allogeneic HIP islets achieve long-term survival.

From: Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

Fig. 6: Allogeneic HIP islets achieve long-term survival.

a, Immunofluorescence pictures of dissociated and reaggregated wtallo and HIPallo islets from rhesus monkeys (representative images). b, In vitro insulin secretion of wtallo and HIPallo islets (mean ± s.d., triplicates). c, The composition of wtallo and HIPallo islets of α, β, δ and other cells (mean, triplicates). d, Flow cytometry histograms for HLA class I and II and rhesus CD47 on wtallo and HIPallo islets (representative images). eh, The survival of FLuc+ wtallo and HIPallo islets in allogeneic rhesus monkeys was followed by BLI (one animal each).

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