Extended Data Fig. 5: Comparison of Cas9 variants with different PAM compatibilities.
From: Deep learning models to predict the editing efficiencies and outcomes of diverse base editors
Maximum average indel frequencies generated by any of the ten Cas9 variants (left heatmaps) and the corresponding Cas9 variants that showed the highest average activities (right heatmaps) at target sequences containing each 4-nt PAM sequence. If the maximum average indel frequencies were lower than 5% (a) and 20% (b), the corresponding candidate PAMs were shown in white.
