Extended Data Fig. 10: Proliferation Ki67+ cells in whole mouse body.
From: Whole-body cellular mapping in mouse using standard IgG antibodies
(a) wildDISCO immunostaining of cell proliferation marker Ki67 (cyan) and PI (magenta) in the whole mouse. (b) Representative 2D optical image of Ki67-positive proliferation cells (cyan) as rare cells compared to nuclear staining (propidium iodide, PI) in the bone marrow (b), vertebrate (c), gut (d) and hippocampus (e). (f–g) Single proliferation cells identified in brain (f) and vertebrate (g) by whole-body light-sheet microscopy scans. Higher magnification images show colocalization of proliferation cells with a single nucleus. n = 3.
