Extended Data Fig. 5: Functional screening in HEK293T and TAM characterization of TnpB systems from de novo annotation. | Nature Biotechnology

Extended Data Fig. 5: Functional screening in HEK293T and TAM characterization of TnpB systems from de novo annotation.

From: Evolutionary mining and functional characterization of TnpB nucleases identify efficient miniature genome editors

Extended Data Fig. 5

a, Two TnpB systems induced reporter activity in HEK293T, as shown in Fig. 3a. Data are shown as the mean ± SD of three biological replicates with actual values overlaid. b, TAM logos for 10 TnpB systems characterized via a negative selection assay in E. coli, as shown in Fig. 2a.

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