Fig. 3: Combined synteny-based and SNP-based analysis of simple microbial populations. | Nature Biotechnology

Fig. 3: Combined synteny-based and SNP-based analysis of simple microbial populations.

From: Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution

Fig. 3

ad, Points represent specific pairwise comparisons; popANI, SNP-based strain similarity, as calculated by inStrain. Red and blue lines show the same-strain cutoffs for SynTracker (>0.955) and inStrain (>0.99999); the same cutoffs are used in each panel. Purple points mark comparisons classified as the same strain by both tools, red points mark comparisons classified as the same strain by SynTrakcer, blue points mark comparisons classified as the same strain by inStrain and gray points are pairs marked as belonging to different strains by both tools. N. gonorrhoeae, n = 66 comparisons (a); hypermutator E. coli, n = 185 comparisons (b); H. pylori clinical isolates (participant 326), n = 91 comparisons (c); S. rimosus M527, n = 185 comparisons (d).

Back to article page