Extended Data Fig. 10: Comparison of human anti-SARS-CoV-2 RBD antibodies isolated in this work with antibodies isolated by LIBRA-seq.
(a) Comparison of affinities (KD). All characterized RBD binders were included in the comparison. For antibodies isolated in this work, the same KD values are depicted in Fig. 3d. Antibody affinity measurements by BLI were performed once but using at least four different analyte concentrations. For antibodies isolated by LIBRA-seq55, previously reported values are shown. Horizontal lines denote the median. (b) Comparison of neutralizing capacities. Only antibodies tested against authentic SARS-CoV-2 were included in the comparison. For antibodies isolated in this work, the same IC50 is depicted in Fig. 3e. Mean values of two technical replicates are shown. For antibodies isolated by LIBRA-seq, previously reported values are shown. Different neutralization assays were used in the two studies.
