Extended Data Fig. 3: Comparison of the transcriptomes of iPSC-derived cells from the HSPC clusters that co-expressed HLF and SPINK2, with those of HLF+SPINK2+ cells from CS14 and CS15 embryos (Part 1). | Nature Biotechnology

Extended Data Fig. 3: Comparison of the transcriptomes of iPSC-derived cells from the HSPC clusters that co-expressed HLF and SPINK2, with those of HLF+SPINK2+ cells from CS14 and CS15 embryos (Part 1).

From: Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells

Extended Data Fig. 3

(a) Nascent HSC. (b) HSC transcription factors. (c) HSC maturation. (d) HSPC waves. (e) Hematopoietic cell identity. Cell numbers: CS14, 51; CS15, 70; PB noR, 489; PB R3-5, 880; PB R3-11 + , 1614; RM noR, 424; RM R3-5, 400; RM R3-14, 288. See also Supplementary Table 5. Abbreviations: PB, PB1.1 BFP; RM, RM TOM. The scorecards developed by the Mikkola laboratory were used as templates13.

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