Extended Data Fig. 6: Comparison of the A-to-G editing and C-to-T editing induced by the TALEDs and DdCBEs with same TALE arrays. | Nature Biotechnology

Extended Data Fig. 6: Comparison of the A-to-G editing and C-to-T editing induced by the TALEDs and DdCBEs with same TALE arrays.

From: Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA

Extended Data Fig. 6: Comparison of the A-to-G editing and C-to-T editing induced by the TALEDs and DdCBEs with same TALE arrays.The alternative text for this image may have been generated using AI.

a, Schematic of the constructions of sTALED and DdCBE targeting mitochondrial DNA. b, A-to-G and C-to-T editing frequencies induced by DdCBE and sTALED at the ND5.1, ND6.1, TRNG, ND4L and ND5.3 sites in 293FT cells. The data are presented as the mean ± s.d. from three independent experiments.

Back to article page