Extended Data Fig. 6: Pathway and community level contributions in skin metatranscriptomes.

(a) Boxplots of core microbial pathways dominated ( > 50% contribution) by Malassezia, Staphylococcus or Cutibacterium. Adjusted p-values for pair-wise Wilcoxon ranked sum tests are shown. Stacked bar plots for species level pathway contributions at RNA level were estimated with HUMAnN3 for (b) beta oxidation of fatty acids, (c) galactose degradation by the Leloir pathway and (d) arginine biosynthesis. Community level relative abundances at RNA level were estimated with Kraken2. Alpha or beta diversity scores≤0.5 were considered “low” diversity.