Extended Data Fig. 10: Correlations between microbial transcript and organism abundances of two distinct species on the same site.
(a) Scatterplot of adjusted p-values and Spearman Rho coefficients derived from correlating Malassezia restricta transcript abundances with Cutibacterium acnes metagenomic abundances across individuals on scalp sites. (b) Scatterplot showing negative correlation between variance stabilized (vst) levels of a transcript from a Barwin domain-containing protein (DNF11_2196) expressed in Malassezia restricta and centered log ratio (clr) abundances of Cutibacterium acnes. (c) Same as (b) but showing the relationship between the transcript and clr abundances of M. restricta. (d) Scatterplot of clr abundances of M. restricta against C. acnes. (e) Volcano plot showing correlation and adjusted p-values of transcripts of C. acnes proteins in the secretory pathway against clr abundances of Cutibacterium granulosum. Statistically significant correlations are highlighted in red. (f) Scatterplot showing negative correlation between levels of a transcript (AAT83849.1) expressed in C. acnes and clr abundances of C. granulosum. (g) Same as (f) but showing the relationship between the transcript and clr abundances of C. acnes.
