Extended Data Fig. 3: Assessing single-nucleotide variants at the ADP-ribosylated thymine targeted with the specified editor. | Nature Biotechnology

Extended Data Fig. 3: Assessing single-nucleotide variants at the ADP-ribosylated thymine targeted with the specified editor.

From: Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes

Extended Data Fig. 3: Assessing single-nucleotide variants at the ADP-ribosylated thymine targeted with the specified editor.The alternative text for this image may have been generated using AI.

Aligned reads are quantified that match the unedited sequence at all positions except at the ADP-ribosylated position as a percent of all aligned reads. Each biological replicate starts from a separate transformation.

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