The COP16 decision established a multilateral mechanism for digital sequence information (DSI) benefit-sharing. This Comment brings together insights from academia and commercial DSI researchers to assess what has been accomplished so far, identify remaining challenges and describe elements under discussion to support collective goals.
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References
UNEP. Conference of the Parties to the Convention on Biological Diversity. Digital sequence information on genetic resources. CBD/COP/DEC/15/9. CBD https://www.cbd.int/doc/decisions/cop-15/cop-15-dec-09-en.pdf (2022).
Halewood, M., Bagley, M. A., Wyss, M. & Scholz, A. H. Science 382, 520–522 (2023).
UNEP. Conference of the Parties to the Convention on Biological Diversity. Digital sequence information on genetic resources. CBD/COP/DEC/16/2. CBD https://www.cbd.int/doc/decisions/cop-16/cop-16-dec-02-en.pdf (2024).
Sara, R., Wyss, M., Custers, R., In ’t Veld, A. & Muyldermans, D. EMBO Rep. 23, e53973 (2022).
Scholz, A. H. et al. Nat. Commun. 13, 1086 (2022).
UNEP. Subsidiary Body on Scientific, Technical and Technological Advice Twenty-sixth meeting. Study on access and benefit-sharing indicators as they relate to target 13 and goal C of the Kunming-Montreal Global Biodiversity Framework. https://www.cbd.int/doc/c/6920/4e1e/8a6ba925279ea19033eb8ed2/sbstta-26-inf-12-en.pdf (2024).
Food and Agriculture Organization of the United Nations. International Treaty on Plant Genetic Resources for Food and Agriculture. https://openknowledge.fao.org/server/api/core/bitstreams/a9d0de2a-8e98-4f75-98a8-673078841030/content (2009).
Van Vooren, B. & Gevrenova, Y. Biosci. L. Rev. 19, 211–227 (2025); https://www.cov.com/-/media/files/corporate/publications/2025/05/resolving-access-and-benefit-sharing-from-biodiversity-towards-an-effective-global-benefit-sharing-mechanism-on-digital-sequence-information.pdf
Conference of the Parties to the Convention on Biological Diversity. The multilateral mechanism for the fair and equitable sharing of benefits from the use of digital sequence information on genetic resources, including a global fund (“The Cali Fund”): submission of views on possible additional modalities of the multilateral mechanism. SCBD/OES/DC/TS/CGA/KB/91971. https://www.cbd.int/doc/notifications/2024/ntf-2024-114-dsi-en.pdf (2024)
Department for Environment, Food & Rural Affairs & Reed, S. UK government gathers business and environment leaders in support of UN nature agreement. https://www.gov.uk/government/news/uk-government-gathers-business-and-environment-leaders-in-support-of-un-nature-agreement (25 June 2025).
UN FCCC. Report of the Conference of the Parties on its twenty-sixth session, held in Glasgow from 31 October to 13 November 2021 – addendum part two: action taken by the Conference of the Parties at its twenty-sixth session. FCCC/CP/2021/12/Add.1 https://unfccc.int/sites/default/files/resource/cp2021_12_add1_adv.pdf (2021).
Sett, S. et al. Nat. Commun. 15, 8745 (2024).
Acknowledgements
The authors thank J. Perrettson, head of partnerships & external engagement at Novonesis, for critical reading of this manuscript and constructive suggestions. A.H.S. was supported by the German Alliance of Scientific Organization’s project “Access and Benefit Sharing Information Platform.” M.J. acknowledges the European Union’s Horizon Europe Programme under grant agreement no. 101082304 (BlueRemediomics). UK partners are supported by UKRI under the UK Government’s Horizon Europe funding guarantee grant no. IFS 10057167 (University of Aberdeen).
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All authors contributed to the ideas presented in this article and contributed to the writing and editing. All authors read and approved the final manuscript.
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M.J. and A.H.S. are members of the DSI Scientific Network. M.J. is co-lead of the Marine Genetic Resources Working group of the Deep Ocean Stewardship Initiative and a member of the World Commission on Protected Areas of the IUCN. A.H.S. is on the leadership team of the IUCN Microbial Conservation Specialist Group. C.B. is employed by Novonesis and serves as co-lead of the DSI subgroup in the ABS Task Force of the International Chamber of Commerce (ICC). J.M.R. is employed by Bayer Crop Science and serves as chair of the ABS Task Force of the ICC, as well as chair of the Coordination Group on Genetic Resources of the International Seed Federation (ISF). All authors are writing in their personal capacities. The views expressed here do not necessarily reflect the views of these groups, institutions and organizations.
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Blom, C., Jaspars, M., Muminovic Rilak, J. et al. From frameworks to finance: how sharing benefits from the use of digital sequence information can evolve to contribute to biodiversity conservation. Nat Biotechnol 43, 1599–1602 (2025). https://doi.org/10.1038/s41587-025-02820-8
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DOI: https://doi.org/10.1038/s41587-025-02820-8